Ursodeoxycholic acid and cancer prevention
نویسندگان
چکیده
منابع مشابه
Ursodeoxycholic acid and chemoprevention of colorectal cancer.
Colorectal cancer is respectively the third and second most common cancer among men and women in France. Interest in chemoprevention for colorectal cancer has increased over the last two decades. Beside non-steroidal anti-inflammatory drugs, ursodeoxycholic acid (UDCA) may have chemopreventive action in colorectal cancer with a likely better tolerance. In high-risk populations such as patients ...
متن کاملUrsodeoxycholic acid
Ursodeoxycholic acid is an epimer of chenodeoxycholic acid (DB06777). It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic. [PubChem] Indication: The drug reduces cholesterol absorption and is used to dis...
متن کاملThe Association of Ursodeoxycholic Acid Use With Colorectal Cancer Risk
Data from preclinical studies suggest that ursodeoxycholic acid (UDCA) has a chemopreventive effect on colorectal cancer (CRC) development, but no large observational study has examined this possibility. The aim of this study was to investigate the association of UDCA use with CRC risk in a nationwide population-based cohort. This nationwide population-based cohort study used data from the Taiw...
متن کاملUrsodeoxycholic acid treatment in a rat model of cancer cachexia
BACKGROUND Cancer cachexia is characterized by loss of both adipose and skeletal muscle tissue and by an increased production of proinflammatory cytokines. Ursodeoxycholic acid (UDCA), a bile acid used for centuries in the treatment of liver disease, is known to confer anti-inflammatory and anti-apoptotic effects as well as beneficial effects on mitochondrial integrity and cell signaling. We hy...
متن کاملControversies in Chemoprevention of Colorectal Cancer with Ursodeoxycholic Acid
Colorectal cancer (CRC) is one of the most common cancers among men and women in western countries. Both in vitro and in vivo data strongly suggest that ursodeoxycholic acid (UDCA), a tertiary bile acid found naturally in low concentrations in humans may protect against CRC. Human studies also suggest that UDCA inhibits tumor development in high-risk subjects and inflammatory bowel disease (IBD...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Council
سال: 2019
ISSN: 2658-5790,2079-701X
DOI: 10.21518/2079-701x-2019-14-39-43